Protein-protein interactions in drug discovery

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of prote...

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Detalles Bibliográficos
Otros Autores: Dömling, Alexander (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Weinheim : Wiley-VCH 2013.
Colección:Wiley ebooks.
Methods and principles in medicinal chemistry ; v. 56.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b46150948*spi
Descripción
Sumario:Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the devel.
Descripción Física:1 recurso electrónico (xxi, 314 páginas) : ilustraciones
Formato:Forma de acceso: World Wide Web.
Bibliografía:Incluye referencias bibliográficas e índice.
ISBN:9783527648238
9783527648207