Mitochondrial replacement techniques : ethical, social, and policy considerations

Mitochondrial replacement techniques ethical, social, and policy considerations

Mostrar otras versiones (1)

Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the tec...

Descripción completa

Detalles Bibliográficos
Autor Corporativo: Institute of Medicine (U.S.). Committee on the Ethical and Social Policy Considerations of Novel Techniques for Prevention of Maternal Transmission of Mitochondrial DNA Diseases (-)
Otros Autores: Claiborne, Anne B., editor (editor), English, Rebecca A., editor, Kahn, Jeffrey P., editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press [2016]
Colección:National Academies ebooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b44942473*spi
Descripción
Sumario:Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration's consideration of investigational new drug applications.
Descripción Física:1 recurso electrónico (xvi, 184 páginas) : ilustraciones
Formato:Forma de acceso: World Wide Web.
Bibliografía:Incluye referencias bibliográficas.
ISBN:9780309388702
9780309388719

Ejemplares similares