Viral Recombination
Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genom...
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| Autor Corporativo: | |
| Formato: | |
| Idioma: | Inglés |
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Cambridge, MA :
MyJoVE Corp
2016.
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| Colección: | JOVE Science Education.
Core Bio. |
| Acceso en línea: | Acceso a vídeo desde UNAV |
| Ver en Universidad de Navarra: | https://innopac.unav.es/record=b42119558*spi |
| Sumario: | Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment. Viral Recombination Can Create New Diseases Some diseases can infect multiple species. For example, pigs can be infected by some human and bird viruses, in addition to the viruses that usually infect pigs. Because viruses can recombine when they co-infect the same cell, pigs can act like zmixing vesselsy that recombine viruses from other species to create new viruses that can sometimes infect humans. This worrisome phenomenon represents a route through which infectious material from other species can enter the human population. Diseases that move from animals to humans are known as zoonoses. Humans can be highly susceptible to such viruses because we have no history of exposure that would have generated immunity. Influenza A is a prime example of the zmixing vessely theory of viral disease. Research has demonstrated that pig, bird, and human influenza A viruses have reassorted inside pig hosts. These events yielded zdouble reassortanty viruses that contained genes from human and bird viruses and ztriple-reassortanty viruses that contained genes from human, bird, and pig viruses. In the Netherlands, a reassortant virus composed of human and bird flu genes was transmitted from pigs to humans. |
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| Notas: | Tít. sacado de la página de descripción del recurso. |
| Descripción Física: | 1 recurso electrónico (51 seg.) : son., col |
| Formato: | Forma de acceso: World Wide Web. |
| Público: | Para estudiantes universitarios, graduados y profesionales. |
