The Biology of Senescence A Translational Approach

This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delin...

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Detalles Bibliográficos
Autor principal: Swynghedauw, Bernard (-)
Autor Corporativo: SpringerLink (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Cham : Springer International Publishing 2019.
Edición:1st ed
Colección:Springer eBooks.
Practical Issues in Geriatrics ;
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b39877759*spi
Descripción
Sumario:This book describes the fundamental process of senescence, and reviews a new concept developed by a number of research groups that is based on cellular senescence and its secretome. This concept provides a basic explanation of the main physiological and pathological features of senescence, and delineates possibilities for ztreatingy it. Following an introduction to the emerging medical landscape, the increasing incidence of a new epidemiological group (age-related zchronic non-transmissible diseasesy), and the multiple origins of aging, the book explores and characterizes the senescent cell, which is linked to benign and pathological age-related manifestations. In turn, the closing chapters discuss how to ztreaty or zpreventy the aging process, underscoring the central role of physical exercise and caloric reduction as compared to new senolytic approaches. Appendices are also provided, and address circadian rhythms, telomere shortening, diabetic cardiomyopathy, and senescence in plants and bacteria. Given its scope, the book will primarily be of interest to geriatricians, but will also appeal to a wider range of clinicians.
Descripción Física:XI, 121 p. : 23 il., 13 il. col
Formato:Forma de acceso: World Wide Web.
ISBN:9783030151119