Genome Mapping and Genomics in Human and Non-Human Primates

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our u...

Descripción completa

Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Duggirala, Ravindranath (-), Almasy, Laura, Williams-Blangero, Sarah, Paul, Solomon F.D, Kole, Chittaranjan
Formato: Libro electrónico
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg 2015.
Colección:Genome Mapping and Genomics in Animals ; 5.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b33005321*spi
Descripción
Sumario:This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates.
Descripción Física:VIII, 305 p., 39 il., 10 il. col
Formato:Forma de acceso: World Wide Web.
ISBN:9783662463062