The UNC-53-mediated Interactome Analysis of its Role in the Generation of the C. elegans Connectome
This book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in tur...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
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Cham :
Springer International Publishing
2014.
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| Colección: | SpringerBriefs in Neuroscience.
Springer eBooks. |
| Acceso en línea: | Conectar con la versión electrónica |
| Ver en Universidad de Navarra: | https://innopac.unav.es/record=b3299915x*spi |
| Sumario: | This book gives an overview of various interactomes involved in dorsal ventral (DV) and anterior posterior (AP) guidance, their mechanisms of action, subcellular localizations, and functional roles. It will provide readers a better understanding of the development of the nervous system, which in turn will help to find cures to various neural and other disorders. In nematodes there are two types of guidance systems, including DV and AP guidance. The signaling process that guides the growth cones along the DV axis has remained intact in both vertebrates and invertebrates. The adaptor protein UNC-53 appears to play a part in migration along the AP axis in both worms and their human homologs. zNeuron Navigatorsy (NAV) are also involved in nervous system development . |
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| Descripción Física: | VI, 87 p., 15 il., 14 il. col |
| Formato: | Forma de acceso: World Wide Web. |
| ISBN: | 9783319078274 |
