Acute Myelogenous Leukemia Genetics, Biology and Therapy

Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Nagarajan, Lalitha (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: New York, NY : Springer New York 2010.
Edición:1st ed
Colección:Cancer Treatment and Research ; 145.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b32853166*spi
Descripción
Sumario:Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as the population ages. Over the past 15 years, genetic mechanisms underlying AML have begun to unfold. Additional research in this area has helped identify key components and characteristics. Consequently, targeted therapy of AML is receiving much attention. It is the hope of researchers that as with chronic myelogenous leukemia (CML), and the drug, Gleevec, a targeted therapy for AML will be discovered. "The effective treatment of acute myelogenous leukemia remains a great challenge. This text reviews our understanding of the molecular and biologic basis of the disease. Leading investigators address advances in prognostication and therapeutic strategies that have significant promise." Steven T. Rosen, M.D. Series Editor.
Descripción Física:IX, 280 p.
Formato:Forma de acceso: World Wide Web.
ISBN:9780387692593