Neuroblastoma Diagnosis, Therapy, and Prognosis

Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnet...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Hayat, M.A (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands 2012.
Colección:Pediatric Cancer ; 1.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b32701342*spi
Descripción
Sumario:Introduction of new technologies and their applications to neuroblastoma diagnosis, treatment, and therapy assessment are explained. Role of molecular ghenetics in diagnosis and therapy for neuroblastoma patients is detailed. Molecular detection of minimal residual neuroblastoma is described. Magnetic resonance imaging and  spectroscopy are detailed for diagnosing this solid, extracranial cancer. Targets for therapeutic intervention in neuroblastoma are identified, including targeting multidrug resistance in this cancer. Ornithine decarboxylase and polyamines are novel targets for therapeutic intervention. The effectiveness of chemotherapy with oral irinotecan and temozolomide is explained. The role of transcription factors (GATA) in neuroblastoma pregression is  also included.
Descripción Física:XVIII, 262 p., 40 il., 24 il. col
Formato:Forma de acceso: World Wide Web.
ISBN:9789400724181