The Extracellular Matrix: an Overview

Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series zBiology of Extracellular Matrixy provides a timely overview of the structure, regulation, and function of the major macromolecules th...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Mecham, Robert P. (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg 2011.
Colección:Biology of Extracellular Matrix.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b32694313*spi
Descripción
Sumario:Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series zBiology of Extracellular Matrixy provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment.  Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Descripción Física:XIV, 426 p.
Formato:Forma de acceso: World Wide Web.
ISBN:9783642165559