Phosphoinositide 3-kinase in Health and Disease Volume 1

From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in pro...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Rommel, Christian (-), Vanhaesebroeck, Bart, Vogt, Peter K.
Formato: Libro electrónico
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg 2011.
Colección:Current Topics in Microbiology and Immunology ; 346.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b32693941*spi
Descripción
Sumario:From humble beginnings over 25 years ago as a lipid kinase activity associated with certain oncoproteins, PI3K (phosphoinositide 3-kinase) has been catapulted to the forefront of drug development in cancer, immunity and thrombosis, with the first clinical trials of PI3K pathway inhibitors now in progress. Here the authors give a brief overview of some key discoveries in the PI3K area and their impact, and include thoughts on the current state of the field, and where it could go from here.
Descripción Física:X, 310 p., 29 il., 23 il. col
Formato:Forma de acceso: World Wide Web.
ISBN:9783642136634