Molecular Analysis of B Lymphocyte Development and Activation

The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell...

Descripción completa

Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Singh, Harinder (-), Grosschedl, Rudolf
Formato: Libro electrónico
Idioma:Inglés
Publicado: Berlin, Heidelberg : Springer Berlin Heidelberg 2005.
Colección:Current Topics in Microbiology and Immunology ; 290.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b3268860x*spi
Descripción
Sumario:The B lymphocyte lineage represents an important paradigm for exploring the molecular mechanisms underlying cell fate specification, differentiation and cellular activation. In the past five years, major advances have been achieved in our understanding of the transcriptional control of early B cell development and terminal plasma cell differentiation. In addition new insights became available for the processes of B cell activation, class switch recombination and somatic hypermutation. Many of the new findings and their implications for a molecular understanding of B cell biology in particular and cell differentiation in general are covered in this volume.
Descripción Física:XI, 260 p.
Formato:Forma de acceso: World Wide Web.
ISBN:9783540263630