Virtual ADMET Assessment in Target Selection and Maturation
Today, biologists and medicinal chemists realize that there is a strong relationship between pharmacodynamic (what the drug does to the organism) and pharmacokinetic (what the organism does to the drug) effects. A significant contributing factor to the evolution in drug discovery was the methodologi...
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
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Amsterdam :
IOS Press
2006.
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| Colección: | EBSCO Academic eBook Collection Complete.
Solvay Pharmaceuticals Conferences ; v. 6. |
| Acceso en línea: | Conectar con la versión electrónica |
| Ver en Universidad de Navarra: | https://innopac.unav.es/record=b31702648*spi |
| Sumario: | Today, biologists and medicinal chemists realize that there is a strong relationship between pharmacodynamic (what the drug does to the organism) and pharmacokinetic (what the organism does to the drug) effects. A significant contributing factor to the evolution in drug discovery was the methodological and technological revolution with the advent of combinatorial chemistry, high-throughput screening and profiling, and in silico prediction of target-based activity and ADMET (absorption, distribution, metabolism, excretion and toxicity) properties. High-throughput screening and in silico methods. |
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| Descripción Física: | 268 p. |
| Formato: | Forma de acceso: World Wide Web. |
| ISBN: | 9781433701559 9781429467728 |
