Osteoarthritis: From Molecular Pathways to Therapeutic Advances

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Osteoarthritis: From Molecular Pathways to Therapeutic Advances

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.

Detalles Bibliográficos
Otros Autores:	Veronese, Nicola (Editor )
Formato:	Libro electrónico
Idioma:	Inglés
Publicado:	Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Materias:	Research & information: general Biology, life sciences osteoarthritis cartilage type II collagen matrix metalloproteinases MMP-13 regulation inhibitor NO synthase Interleukin-1β chondrocytes mitochondrial dysfunction mesenchimal stem cells chondrocytic commitment autophagy miRNAs hydrostatic pressure adipokines visfatin Wnt/β-catenin mechanical loading obesity microRNA oxidative stress vibrational spectroscopy near-infrared spectroscopy infrared spectroscopy Raman spectroscopy early diagnosis exercise physical activity nutraceuticals dietary supplements inflammation aging inflammaging osteochondral explant culture joint modelling pharmacological assay native tissue analysis hexosamine biosynthetic pathway cartilage trauma post-traumatic osteoarthritis O-GlcNAcylation glucosamine cell death therapy sex as a biological variable whole transcriptome sequencing molecules TGF-β SMAD2/3 signaling linker modifications meniscus proteomics MRM ECM celecoxib glucosamine sulfate chondroprotection NF-κB cytokines chemokines pathogenesis biomarker chondrocyte IL-1β IFNγ, IL-17 IL-4 RNA-Seq hypertrophy remodeling angiogenesis chondroitin collagen methylsulfonylmethane vitamin C vitamin D hyaluronic acid
Ver en Biblioteca Universitat Ramon Llull:	https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009660402406719

Descripción
Sumario:	In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.
Descripción Física:	1 electronic resource (306 p.)