Brain tumors and the Lynch syndrome
Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is est...
| Otros Autores: | , |
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| Formato: | Capítulo de libro electrónico |
| Idioma: | Inglés |
| Publicado: |
IntechOpen
2011
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009653940306719 |
| Sumario: | Lynch syndrome (LS) (MIM No. 120435-6), previously known as hereditary nonpolyposis colorectal cancer (HNPCC) (Boland, 2005), is an autosomal dominant disorder caused by germline mutation in one of the DNA mismatch repair (MMR) genes. LS is among the most prevalent cancer syndromes in man and is estimated to account for 1-6% of all colorectal cancers (Lynch & de la Chapelle, 2003). |
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| Descripción Física: | 1 online resource (chapter 15, pages [363]-382) : illustrations; digital file(s) |
| Bibliografía: | Includes bibliographical references. |
| ISBN: | 9789535165033 |
