Neurobiology of Huntington's disease applications to drug discovery
In 1993, the genetic mutation responsible for Huntington's disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse...
| Otros Autores: | , |
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| Formato: | Libro electrónico |
| Idioma: | Inglés |
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Boca Raton :
CRC Press/Taylor & Francis Group
2010.
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| Colección: | Frontiers in neuroscience (Boca Raton, Fla.)
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| Materias: | |
| Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009621456606719 |
| Sumario: | In 1993, the genetic mutation responsible for Huntington's disease (HD) was identified. Considered a milestone in human genomics, this discovery has led to nearly two decades of remarkable progress that has greatly increased our knowledge of HD, and documented an unexpectedly large and diverse range of biochemical and genetic perturbations that seem to result directly from the expression of the mutant huntingtin gene. Neurobiology of Huntington's Disease: Applications to Drug Discovery presents a thorough review of the issues surrounding drug discovery and development for the treatment of this |
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| Notas: | Description based upon print version of record. |
| Descripción Física: | 1 online resource (342 p.) |
| Bibliografía: | Includes bibliographical references and index. |
| ISBN: | 9781138116627 9780429122255 9781420008258 |
