Tertiary Lymphoid Organs (TLOs): Powerhouses of Disease Immunity

The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A bette...

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Detalles Bibliográficos
Otros Autores: Changjun Yin (auth), Andreas J.R. Habenicht, Pasquale Maffia, Sarajo Mohanta
Formato: Libro electrónico
Idioma:Inglés
Publicado: Frontiers Media SA 2017
Colección:Frontiers Research Topics
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009436031906719
Descripción
Sumario:The immune system employs TLOs to elicit highly localized and forceful responses to unresolvable peripheral tissue inflammation. Current data indicate that TLOs are protective but they may also lead to collateral tissue injury and serve as nesting places to generate autoreactive lymphocytes. A better comprehension of these powerhouses of disease immunity will likely facilitate development to unprecedented and specific therapies to fight chronic inflammatory diseases.
Descripción Física:1 electronic resource (235 p.)