Pain management and the opioid epidemic : balancing societal and individual benefits and risks of prescription opioid use

Pain management and the opioid epidemic balancing societal and individual benefits and risks of prescription opioid use

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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the risi...

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Detalles Bibliográficos
Autor principal: National Academies of Sciences, Engineering, and Medicine.
Autor Corporativo: National Academies of Sciences, Engineering, and Medicine. Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse (-)
Otros Autores: Bonnie, Richard J., editor (editor), Ford, Morgan A., editor, Phillips, Jonathan (Public health researcher), editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, DC : The National Academies Press [2017]
Colección:National Academies ebooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b44944780*spi
Tabla de Contenidos:
  • 1. Introduction; Study Charge
  • Study Approach
  • Definitions and Terminology
  • Study Context
  • Study Scope and Emphasis and Report Organization
  • References
  • PART I PAIN MANAGEMENT AND RESEARCH: 2. Pain Management And The Intersection Of Pain And Opioid Use Disorder; The Scope of the Problem of Pain
  • Opioid Analgesics
  • Nonopioid Pharmacologic Treatments
  • Interventional Pain Therapies
  • Nonpharmacologic Treatments
  • Differences in Pain Experiences and Treatment Effectiveness Among Subpopulations
  • The Intersection Between Pain and Opioid Use Disorder
  • References
  • 3. Progress And Future Directions In Research On Pain And Opioid Use Disorder; Basic Pain Research
  • The Neurobiology of the Reward Pathway and the Intersection of Pain and Opioid Use Disorder
  • Preclinical and Translational Research
  • Clinical Research
  • Intersection of Pain and Opioid Use Disorder
  • Support for Research
  • Summary and Recommendation
  • References
  • PART II ADDRESSING THE OPIOID EPIDEMIC: 4. Trends In Opioid Use, Harms, And Treatment; Trends in Prescription Opioid Use and Misuse
  • Heroin Use and Its Relation to Prescription Opioid Use
  • Illicit Opioid Markets
  • The Current State of Surveillance Systems
  • Recent Developments in Pharmaceutical Treatment of Opioid Use Disorder
  • Trends in Treatment of Opioid Overdose with Naloxone
  • Summary and Recommendations
  • References
  • 5. Evidence On Strategies For Addressing The Opioid Epidemic; Nature of the Evidence
  • The Need for a Systems Approach
  • Strategies for Restricting Supply
  • Strategies for Influencing Prescribing Practices
  • Strategies for Reducing Demand
  • Strategies for Reducing Harm
  • Summary and Recommendations
  • References
  • 6. Opioid Approval And Monitoring By The U.S. Food And Drug Administration; Overview of the FDA's Regulatory Process for Prescription Drugs and Its Application to Opioids
  • Public Health Dimensions of FDA Drug Regulation
  • Key Elements of an Integrated Decision-Making Framework for Opioid Regulation
  • Implementation of an Integrated Framework for Opioid Regulation
  • Summary and Recommendations
  • References
  • Annex Table : Extended-Release(ER)/Long-Acting (LA) Opioid Post-Marketing Study Requirements.

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