An assessment of the NIH Women's Health Initiative
| Autor Corporativo: | |
|---|---|
| Otros Autores: | , |
| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Washington, D.C. :
National Academy Press
1993.
|
| Colección: | National Academies ebooks.
|
| Acceso en línea: | Conectar con la versión electrónica |
| Ver en Universidad de Navarra: | https://innopac.unav.es/record=b44913874*spi |
Tabla de Contenidos:
- Executive summary
- Women's health initiative
- IOM study
- Findings and suggestions
- Clinical trial
- Observational study
- Community prevention study
- Recommendations
- Responses to the statement of task
- Description of the NIH women's health initiative
- History of Institute of Medicine involvement
- Committee selection and participation
- Statement of task
- Committee activities
- Clinical trial
- Rationale
- General issues
- Integration of the CT with other components of the WHI
- Design and methods
- Factorial design
- Sample characteristics
- Proposed analytic techniques
- Ethics: consent and stopping rules
- Minority analysis plan
- Specifying the relationship of intervention an effect
- Outcome definition and measurement
- Recruitment and retention
- Adherence
- Secular trends
- Provision of health care services to participants
- Study management
- Dietary modification branch
- Rationale
- Design and methods
- Weighing benefits and uncertainties of the breast cancer arm
- Hormone replacement therapy branch
- Rationale
- Design and methods.
- (cont) Threats to completion of HRT branch
- Use of HRT in elderly women
- Calcium and vitamin D supplement branch
- Rationale
- Design and methods
- Threats to successful completion of CaD branch
- Clinical trial cost
- Data available to committee deliberations
- WHI cost relative to other larger studies
- Clinical center funding
- Total cost
- Potential causes of budget shortfalls
- Observational study
- Rationale
- Design and method
- Cost
- Recommendations
- Community prevention study
- Rationale
- Design and methods
- Cost
- Recommendations
- Concluding remarks
- Response to the statement of task
- Societal context
- Efficacy and effectiveness
- Public health choice versus individual choice
- Considerations beyond science
- Clinical trial exclusion criteria
- U.S. House of Representatives Appropriations Committee
- Statement of task
- Documents received by the Institute of Medicine from the National Institutes of Health
- Meeting participants June, July and August 1993
- Primary and subsidiary hypotheses of the women's health initiative clinical trial.
- (cont) Women's health initiative committees
- NIH-sponsored women's health studies
- NIH cost and FTE summary for Vanguard clinical centers
- NIH power calculations
- Women's health initiative clinical coordinating center and Vanguard clinical centers principal investigators
- Abbreviations and acronyms
- Committee and staff biographies.
