Targeting Protein-Protein Interactions by Small Molecules
This book comprehensively reviews the state-of-the-art strategies developed for protein-protein interaction (PPI) inhibitors, and highlights the success stories in new drug discovery and development. Consisting of two parts with twelve chapters, it demonstrates the design strategies and case studies...
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| Otros Autores: | , |
| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Singapore :
Springer Singapore : Imprint: Springer
2018.
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| Colección: | Springer eBooks.
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| Acceso en línea: | Conectar con la versión electrónica |
| Ver en Universidad de Navarra: | https://innopac.unav.es/record=b38048206*spi |
Tabla de Contenidos:
- Part 1 Current strategies for the discovery of small-molecule inhibitors of protein-protein interactions
- Overview of Protein-protein Interactions and Small Molecule Inhibitors under Clinical Development
- High throughput screening in the discovery of small molecule inhibitors of protein-protein interactions
- Hot Spot-Based Design of Small-Molecule Inhibitors for Protein-Protein Interactions
- Computational Methods Applicable to the Discovery of Small-Molecule Inhibitors of Protein-Protein Interactions
- Experimental Methods Used for Identifying Small-Molecule Inhibitors of Protein-protein Interaction
- Fragment-based Drug Discovery for Developing Inhibitors of Protein-protein Interactions
- Part 2 Case studies of small-molecule inhibitors of protein-protein interactions
- Small molecule inhibitors targeting new targets of protein-protein interactions
- The Development of New Spirooxindoles Targeting the p53-MDM2 Protein-Protein Interactions for Cancer Therapy
- Small-Molecule Inhibitors for the Ý-Catenin/T-Cell Factor Protein−Protein Interaction
- Discovery and development of Keap1-Nrf2 protein-protein interaction inhibitors
- BRDT Inhibitors for Male Contraceptive Drug Discovery: Current Status
- Targeting Protein-Protein Interactions in Small GTPases.
