The Role of Pendrin in Health and Disease Molecular and Functional Aspects of the SLC26A4 Anion Exchanger
This book reviews the current state of knowledge on the genetics, molecular biology and physiology of pendrin, with a particular focus on pendrin dysfunction and the consequences for human health. Pendrin is a membrane transport protein expressed in the thyroid, inner ear, kidney and airways, and wa...
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| Otros Autores: | , |
| Formato: | Libro electrónico |
| Idioma: | Inglés |
| Publicado: |
Cham :
Springer International Publishing
2017.
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| Colección: | Springer eBooks.
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| Acceso en línea: | Conectar con la versión electrónica |
| Ver en Universidad de Navarra: | https://innopac.unav.es/record=b35693216*spi |
Tabla de Contenidos:
- Pendrin and the Pendrin Consortium
- Pendrin role in the inner ear
- Pendrin role in the thyroid and Pendred syndrome
- Pendrin role in the kidney and hypertension
- Interplay between Pendrin and other renal transport molecules
- Pendrin role in the airways: links with asthma and COPD
- Pendrin expression and function in non-conventional sites
- Transcriptional regulation and epigenetics of Pendrin
- Models for Pendrin structure
- Genetic diagnosis of deafness
- Functional and molecular properties of Pendrin allelic variants
- Potential pharmacological interventions for Pendrin dysfunction.
