Systems Biology Integrative Biology and Simulation Tools
Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing...
Autor Corporativo: | |
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Otros Autores: | , |
Formato: | Libro electrónico |
Idioma: | Inglés |
Publicado: |
Dordrecht :
Springer Netherlands
2013.
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Colección: | Springer eBooks.
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Acceso en línea: | Conectar con la versión electrónica |
Ver en Universidad de Navarra: | https://innopac.unav.es/record=b33008632*spi |
Tabla de Contenidos:
- Functional genomics, proteomics, metabolomics and bioinformatics for systems biology
- Comparing biological networks: a survey on graph classifying techniques
- Emergent properties of gene regulatory networks – models and data
- Regulatory crosstalk analysis of biochemical networks in the nucleus accumbens
- Properties of biological networks
- Network analysis for systems biology
- Computational approaches for reconstruction of time-varying biological networks from Omics data
- Probabilistic graphical modeling in systems biology: a framework for integrative approaches
- Innovations of the rule-based modeling approach
- Reproducibility of model-based results in systems biology
- Parameter identifiability and redundancy, with applications to a general class of stochastic carcinogenesis models
- Semantic systems biology: formal knowledge representation in systems biology for model construction, retrieval, validation and discovery
- Computational infrastructures for data and knowledge management in systems biology
- Computational tools and resources for integrative modeling in systems biology
- Agent-based modeling approaches to multi-scale systems biology: An example agent-based model of acute pulmonary inflammation
- Reconstructing cellular signaling and regulatory networks - an integrative approach for systems-level drug discovery
- A survey of current integrative network algorithms for systems biology
- Direct Computer Mapping based modeling of a multiscale process, involving p53/miR-34a signaling.