Systems Biology Integrative Biology and Simulation Tools

Growth in the pharmaceutical market has slowed down – almost to a standstill. One reason is that governments and other payers are cutting costs in a faltering world economy. But a more fundamental problem is the failure of major companies to discover, develop and market new drugs. Major drugs losing...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Prokop, Aleš (-), Csukás, Béla
Formato: Libro electrónico
Idioma:Inglés
Publicado: Dordrecht : Springer Netherlands 2013.
Colección:Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b33008632*spi
Tabla de Contenidos:
  • Functional genomics, proteomics, metabolomics and bioinformatics for systems biology
  • Comparing biological networks: a survey on graph classifying techniques
  • Emergent properties of gene regulatory networks – models and data
  • Regulatory crosstalk analysis of biochemical networks in the nucleus accumbens
  • Properties of biological networks
  • Network analysis for systems biology
  • Computational approaches for reconstruction of time-varying biological networks from Omics data
  • Probabilistic graphical modeling in systems biology: a framework for integrative approaches
  • Innovations of the rule-based modeling approach
  • Reproducibility of model-based results in systems biology
  • Parameter identifiability and redundancy, with applications to a general class of stochastic carcinogenesis models
  • Semantic systems biology: formal knowledge representation in systems biology for model construction, retrieval, validation and discovery
  • Computational infrastructures for data and knowledge management in systems biology
  • Computational tools and resources for integrative modeling in systems biology
  • Agent-based modeling approaches to multi-scale systems biology: An example agent-based model of acute pulmonary inflammation
  • Reconstructing cellular signaling and regulatory networks - an integrative approach for systems-level drug discovery
  • A survey of current integrative network algorithms for systems biology
  • Direct Computer Mapping based modeling of a multiscale process, involving p53/miR-34a signaling.