Nuclear Signaling Pathways and Targeting Transcription in Cancer

This book presents the most up-to-date information in the area of targeted therapeutics with a particular focus on pathway-centered approaches and transcription by leading authorities in molecular cancer research. The goal is to cover several critical principles of cancer therapeutics, ranging from...

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Detalles Bibliográficos
Autor Corporativo: SpringerLink (-)
Otros Autores: Kumar, Rakesh (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: New York, NY : Springer New York 2014.
Colección:Cancer Drug Discovery and Development.
Springer eBooks.
Acceso en línea:Conectar con la versión electrónica
Ver en Universidad de Navarra:https://innopac.unav.es/record=b3299557x*spi
Tabla de Contenidos:
  • Preface
  • Steroid Receptor Coactivators (SRCs) as Integrators of Multiple Signaling Pathways in Cancer Progression
  • Role of Alteration/Deficiency in Activation (ADA) Complex in the Cell Cycle, Genomic Instability and Cancer
  • RUNX2 Transcriptional Regulation in Development and Disease
  • Epigenetic Mechanisms of Cancer Metastasis
  • Regulatory Effects of Arsenic on Cellular Signaling Pathways: Biological Effects and Therapeutic Implications
  • Nuclear Factors Linking Cancer and Inflammation
  • Regulation of the Jak/STATs Pathways by Histone Deacetylases
  • Receptor Tyrosine Kinases in the Nucleus: Nuclear Functions and Therapeutic Implications in Cancers
  • Nucleolar Signaling Determines Cell Fate – The RP-Mdm2-p53 Axis Fine-Tunes Cellular Homeostasis
  • Transcriptional Regulation of Lipogenesis as a Therapeutic Target for Cancer Treatment
  • Selective Inhibition of Acetyl-Lysine Effector Domains of the Bromodomain Family in Oncology
  • Domain Specific Targeting of Cancer
  • The Potential of Targeting Splicing for Cancer Therapy
  • Exploiting Cell Cycle Pathways in Cancer Therapy: New (and Old) Targets and Potential Strategies
  • Histone Demethylases in Prostate Cancer
  • Therapeutic Significance of Chromatin Remodeling Complexes in Cancer
  • Index.