Possible health effects of exposure to residential electric and magnetic fields

Detalles Bibliográficos
Autor principal: National Research Council (U.S.).
Autor Corporativo: National Research Council (U.S.). Committee on the Possible Effects of Electromagnetic Fields on Biologic Systems (-)
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press 1997.
Edición:1st ed
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009820305106719
Tabla de Contenidos:
  • Possible Health Effects of Exposure to Residential Electric And Magnetic Fields
  • Copyright
  • Preface
  • OTHER REPORTS OF THE COMMISSION ON LIFE SCIENCES
  • Acknowledgments
  • Contents
  • Executive Summary
  • CHARGE TO THE COMMITTEE
  • CONCLUSIONS OF THE COMMITTEE
  • STUDY FINDINGS
  • Epidemiology
  • Exposure Assessment
  • In Vitro Studies on Exposure to Electric and Magnetic Fields
  • In Vivo Studies on Exposure to Electric and Magnetic Fields
  • 1 Introduction
  • BACKGROUND
  • SCOPE OF THE STUDY
  • AREAS OF CONCERN
  • DEFINITIONS AND DESCRIPTIONS OF TERMS
  • Electric and Magnetic Fields
  • Biologic Effects
  • Health Effects
  • Exposure Assessment in Epidemiologic Studies
  • Risk Assessment
  • SOURCES OF EXPOSURE
  • Electric Power Lines
  • Electric Appliances
  • Transportation Systems
  • WHY KNOWLEDGE ABOUT ELECTRIC AND MAGNETIC FIELDS IS IMPORTANT
  • RELATED REPORTS
  • ORGANIZATION OF THIS REPORT
  • 2 Exposure and Physical Interactions
  • SUMMARY AND CONCLUSIONS
  • DEFINITION OF TERMS
  • METHODS OF EXPOSURE ASSESSMENT
  • General Problems
  • Measurement Methods and Instrumentation
  • Field Calculations
  • TYPICAL EXPOSURES
  • Electric Fields
  • Residential and Environmental Magnetic Fields
  • Residence
  • Background Fields
  • Appliances
  • Personal Monitoring
  • Environmental Fields
  • Power Lines (Transmission and Distribution)
  • Occupational Magnetic Fields
  • Workplace
  • Personal Monitoring
  • Transportation
  • Transients
  • EXPOSURES IN EPIDEMIOLOGIC STUDIES
  • Residential
  • Wire Codes
  • Calculations
  • Distance
  • Measurements
  • Occupational
  • EXPOSURES IN LABORATORY EXPERIMENTS
  • Animal and Cellular Studies
  • In Vivo Studies
  • In Vitro Studies
  • INDUCED FIELDS AND CURRENTS
  • Electric-Field Exposure
  • Magnetic-Field Exposure
  • 3 Cellular and Molecular Effects
  • SUMMARY AND CONCLUSIONS.
  • UTILITY AND LIMITATIONS OF IN VITRO STUDIES
  • GENOTOXICITY AND CARCINOGENIC POTENTIAL OF POWER-FREQUENCY ELECTRIC AND MAGNETIC FIELDS
  • EXPERIMENTAL STUDIES OF IN VITRO EFFECTS
  • Heritable Changes in Cells Exposed In Vitro to Electric and Magnetic Fields
  • Transient Changes in Cells Exposed In Vitro to Electric and Magnetic Fields
  • Signal Transduction
  • Gene Expression and Protein Synthesis
  • Calcium Changes
  • 4 Animal and Tissue Effects
  • SUMMARY AND CONCLUSIONS
  • CRITERIA FOR CONSIDERATION OF LITERATURE
  • USE OF ANIMAL STUDIES IN EVALUATING RISK
  • Types of Animal Studies Used in Descriptive Toxicology
  • Acute Lethality
  • Repeated-Dose Studies
  • Subchronic Toxicity Studies
  • Chronic Toxicity Studies
  • Developmental and Reproductive Studies
  • Cocarcinogenicity and Copromotion Studies of Electric and Magnetic Fields
  • CARCINOGENIC AND MUTAGENIC EFFECTS
  • Complete Carcinogen Studies
  • Tumor-Initiation Studies
  • Tumor-Promotion Studies
  • REPRODUCTIVE AND DEVELOPMENTAL EFFECTS
  • Nonmammalian Studies of 50- or 60-Hz Electric Fields
  • Fish
  • Chicken
  • Mammalian Studies of 50- or 60-Hz Electric Fields
  • Mice
  • Rats
  • Swine
  • Cattle
  • Nonmammalian Studies of Time-Varying Magnetic Fields
  • Chicken
  • Mammalian Studies of Time-Varying Magnetic Fields
  • Mice
  • Rats
  • Summary of Reproductive and Developmental Effects
  • NEUROBEHAVIORAL EFFECTS
  • Electric Fields
  • Magnetic Fields
  • Summary of Neurobehavioral Effects
  • IN VIVO NEUROCHEMICAL AND NEUROENDOCRINE EFFECTS
  • Neurochemical Effects
  • Melatonin Effects
  • Effects of Electric Fields on Animals
  • Effects of Magnetic Fields on Animals
  • Effects of Combined Electric and Magnetic Fields on Animals
  • Effects of Electric and Magnetic Fields on Humans
  • Neuroendocrine Effects
  • Consistency and Plausibility of Results
  • BONE HEALING AND STIMULATED CELL GROWTH.
  • Regulation and Cell Biology of Bone
  • Endogenous electromagnetic Properties of Bone
  • Clinical Stimulation of Bone Healing with Electric and Magnetic Fields
  • Potential Mechanisms of Electric-and Magnetic-Field Effects on Bone
  • Effects of Electric and Magnetic Fields on Signal Transduction in Bone
  • A Hypothetical Scenario for Electric-and Magnetic-Field Effects on Bone
  • DISCUSSION
  • 5 Epidemiology
  • SUMMARY AND CONCLUSIONS
  • INTERPRETATION OF EPIDEMIOLOGIC EVIDENCE
  • Potential Sources of Error in Epidemiologic Studies
  • Random Error
  • Information Bias: Misclassification of Disease or Exposure
  • Selection Bias
  • Confounding and Effect Modification
  • Criteria for Causality in Epidemiologic Studies
  • CANCER EPIDEMIOLOGY-RESIDENTIAL EXPOSURES
  • Summary of Evidence
  • Framework for the Interpretation of Evidence Linking Magnetic Fields to Childhood Cancer
  • Are Wire Codes Associated with Cancer?
  • Assessing the Association Between Residential Magnetic Fields and Childhood Leukemia Using Technique of Meta-Analysis to...
  • Methods
  • Results
  • Discussion
  • Selection Bias and Control Selection in Residential Childhood Cancer Studies
  • Information Bias in Residential Childhood Cancer Studies
  • Conclusions on an Association Between Electric Wiring Near Residences and Childhood Cancer
  • Is the Association of Cancer with Electric Wiring Near Residences Accounted for by Factors Other Than Magnetic Fields?
  • Wire Codes and Potential Confounders
  • Cancer and Potential Confounders
  • Evidence of Confounding in Previous Studies
  • Conclusions About Confounding
  • Is the Association with Cancer Accounted for by Magnetic Fields?
  • Review of Exposure-Assessment Methods in Residential Studies
  • Evidence Linking Magnetic Fields to Cancer
  • Evaluation of Epidemiologic Evidence.
  • Quality of Magnetic-Field Indicators and Strength of Association
  • Dose-Response Gradients
  • Confounding
  • Consistency with Secular Trend Data
  • CANCER EPIDEMIOLOGY-APPLIANCE EXPOSURES
  • CANCER EPIDEMIOLOGY-OCCUPATIONAL EXPOSURES
  • REPRODUCTION AND DEVELOPMENT
  • Video-Display Terminals
  • Residences
  • Electric Appliances
  • Workplaces
  • Methodologic Issues
  • LEARNING AND BEHAVIOR
  • Suicide
  • Depression
  • Headaches
  • Neuropsychologic Performance
  • Summary
  • 6 Risk Assessment
  • SUMMARY AND CONCLUSIONS
  • RISK ASSESSMENT
  • Hazard Identification
  • Dose-Response Assessment
  • Exposure Assessment
  • Risk Characterization
  • Biologic Mechanism of Action
  • Overall Conclusions for Risk Assessment
  • Other Possible Human-Health Effects
  • 7 Research Needs and Research Agenda
  • EPIDEMIOLOGIC STUDIES
  • Wire Codes and Childhood Cancer
  • Wire Codes and Confounders
  • Confounders and Childhood Cancer
  • Wire Codes and Magnetic Fields
  • Magnetic Fields and Childhood Cancer
  • Improved Studies of Measured Residential Magnetic Fields and Childhood Cancer
  • Studies of Magnetic Fields from Sources Other Than Power Lines
  • LABORATORY STUDIES
  • Engineering Studies
  • Instrumentation and Transient Currents
  • Biophysical Modeling
  • Wire Codes
  • Grounding System Currents
  • Contemporary Versus Historical Exposures
  • Wire Codes Versus Contemporary and Historical Magnetic-Field Measurements
  • Biologic Studies
  • RESEARCH STRATEGY
  • Appendix A Tables
  • Appendix B Exposure Assessment in Residential Studies
  • WIRE CODES
  • Magnetic-Field Measurements
  • Wire Codes And Residential Magnetic Fields
  • Prediction of Mean Fields and Variance in Fields
  • Prediction of Categories of Fields
  • Wire Codes And Personal Exposure To Magnetic Fields
  • Refinements in Wire Codes
  • Historical Versus Contemporary Measurements.
  • Variability in the Wire-Code and Magnetic-Field Association
  • Alternative Magnetic-Field Indices
  • Wire Codes And Transient And Variable Fields
  • References
  • Glossary
  • Biographic Sketches of Committee Members
  • Index.