Building Confidence in New Evidence Streams for Human Health Risk Assessment : Lessons Learned from Laboratory Mammalian Toxicity Tests

Building Confidence in New Evidence Streams for Human Health Risk Assessment Lessons Learned from Laboratory Mammalian Toxicity Tests

As part of its core mission, the U.S. Environmental Protection Agency (EPA) is tasked with assessing the hazards and risks to human health from exposure to pollutants. While some pollutants are well studied, there are little or no data on the potential health effects for many thousands of chemicals...

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Detalles Bibliográficos
Autor principal: National Academies of Sciences, Engineering, and Medicine (author)
Autor Corporativo: National Academies of Sciences, Engineering, and Medicine, author (author)
Otros Autores: Studies, Division on Earth and Life (-), Research, Institute for Laboratory Animal, Toxicology, Board on Environmental Studies and, Assessment, Committee on Variability and Relevance of Current Laboratory Mammalian Toxicity Tests and Expectations for New Approach Methods (NAMs) for use in Human Health Risk
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academies Press 2024.
Edición:1st ed
Colección:Consensus study report
Materias:
Health risk assessment > United States.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009803437706719
Tabla de Contenidos:
  • Intro
  • Front Matter
  • Summary
  • 1 Introduction
  • 2 Background and Definitions
  • 3 Variability
  • 4 Concordance with Human Data
  • 5 Issues in Developing a Scientific Confidence Framework for NAMs
  • Appendix A: Committee, Staff, and Consultant Biographies
  • Appendix B: Open Session Agendas
  • Appendix C: Evidence Review: Approach, Methods, and Results
  • Appendix D: Selected Examples of Scientific Confidence Frameworks for NAMs.

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