Test No. 319B Determination of in vitro intrinsic clearance using rainbow trout liver S9 sub-cellular fraction (RT-S9)
The Test Guideline (TG) describes the use of liver S9 sub-cellular fraction (RT-S9) of rainbow trout (Oncorhynchus mykiss) as a metabolising system to determine the clearance (CL, IN VITRO, INT ) of a test chemical using a substrate depletion approach. Introduction of the test chemical to the RT-S9...
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Formato: | Libro electrónico |
Idioma: | Inglés |
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Paris, France :
Organisation for Economic Co-operation and Development (OECD) Publishing
2018.
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Colección: | OECD Guidelines for the Testing of Chemicals, Section 3
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Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009704656506719 |