Lead generation approaches in drug discovery
An integrated overview of modern approaches to lead discovery Lead generation is increasingly seen as a distinct and success-determining phase of the drug discovery process. Over recent years, there have been major advances in the understanding of what constitutes a good lead compound and how to imp...
Otros Autores: | , |
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Formato: | Libro electrónico |
Idioma: | Inglés |
Publicado: |
Hoboken, NJ :
Wiley
c2010.
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Edición: | 1st ed |
Materias: | |
Ver en Biblioteca Universitat Ramon Llull: | https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009665119606719 |
Tabla de Contenidos:
- LEAD GENERATION APPROACHES IN DRUG DISCOVERY; CONTENTS; PREFACE; CONTRIBUTORS; 1 Lead Discovery: The Process; 2 High Throughput Screening Approach to Lead Discovery; 3 In Silico Screening; 4 Fragment-Based Lead Discovery; 5 Design of Multitarget Ligands; 6 De novo Drug Design; 7 Role of Natural Products in Drug Discovery; 8 Early Screening for ADMET Properties; 9 Role of Chemistry in Lead Discovery; INDEX