Antimicrobial resistance : issues and options : workshop report

Antimicrobial resistance issues and options : workshop report

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Detalles Bibliográficos
Autor Corporativo: Institute of Medicine (U.S.). Forum on Emerging Infections (-)
Otros Autores: Harrison, Polly F. (-), Lederberg, Joshua
Formato: Libro electrónico
Idioma:Inglés
Publicado: Washington, D.C. : National Academy Press 1998.
Edición:1st ed
Materias:
Drug resistance in microorganisms.
Antibiotics.
Emerging infectious diseases > Chemotherapy.
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009622124006719
Tabla de Contenidos:
  • Antimicrobial Resistance: Issues and Options
  • Copyright
  • Preface
  • THE FORUM
  • THE REPORT AND ITS ORGANIZATION
  • ACKNOWLEDGMENTS
  • NOTES
  • Contents
  • Workshop Summary
  • INTRODUTION
  • ISSUSE AND OPTIONS
  • Workshop Report
  • INTRODUCTION
  • The Topic
  • The Workshop
  • THE COSTS OF ANTIMICROBIAL RESISTANCE
  • Background
  • Recent Case Material
  • TRACKING THE PROBLEM: CURRENT APPROACHES TO SURVEILLANCE
  • Characteristics of an Ideal Resistance Surveillance System
  • Local-Level Surveillance
  • National Systems
  • The United States Centers for Disease Control and Prevention
  • The Surveillance Network
  • The Canadian System
  • The Icelandic Surveillance System
  • International Systems
  • CEM/NET
  • World Health Organization (WHO) Initiatives
  • SENTRY
  • Surveillance and the Laboratory
  • What Is Needed
  • System Design Issues
  • Funding for Surveillance
  • HOW CAN THE SCIENCES HELP?
  • Implications of Mapping the Genome
  • Molecular Detection of Genes Associated with Antimicrobial Resistance
  • Limitations of Phenotype-Based Detection Methods
  • Knowledge About the Genetic Basis of Resistance
  • Advantages and Limitations of Genotype-Based Antimicrobial Resistance Detection
  • High-Density Oligonucleotide Arrays
  • Applications of Genomics and Bioinformatics to the Development of Anti-Infectives
  • A Role for New Therapeutic Approaches in Combating Antimicrobial Resistance
  • Applications of Field Surveillance in the United States and Globally
  • What Is Needed
  • SOURCES OF RESISTANCE AND ANTIBIOTIC USE
  • Sources of Resistance
  • Antibiotic Use
  • The Hospital
  • The Community
  • The Farm
  • Factors in Inappropriate Use of Antibiotics
  • Strategies for Judicious Antibiotic Use
  • RESISTANCE AND FOOD PRODUCTION: ISSUES AND NEEDS
  • Concerns and Perspectives from Producers
  • A National Surveillance System.
  • Strengthened Professional and Public Education
  • Increased Research
  • The Ecology of Resistance on the Farm
  • U.S. Department of Agriculture
  • U.S. Environmental Protection Agency
  • Areas for Consideration and Action in Food Production
  • Collaboration
  • Research
  • Education
  • LEGAL AND REGULATORY CONCERNS
  • Matters of Law and Possible Responses
  • Surveillance
  • Rational Use of Antimicrobial Drugs
  • Research and Development
  • Intellectual Property Protection
  • New Products
  • Existing Products and Compounds
  • Targeted Drug Development
  • Collaborative Research and Development
  • Regulatory FDA Responses to Antimicrobial Resistance
  • Restricted Distribution
  • SUMMARY OF AREAS FOR CONSIDERATION
  • Surveillance
  • Information Systems
  • Laboratory Systems
  • Law and Regulation
  • Response: Prolonging Effectiveness
  • Education
  • Law and Regulation
  • Response: Developing New Products
  • Incentives for Industry
  • Research
  • Education
  • Agricultural Use
  • Research
  • FINAL COMMENTS
  • NOTES
  • APPENDIX A Inventory of Surveillance Systems
  • DOMESTIC ANTIMICROBIAL SURVEILLANCE ACTIVITIES
  • United States
  • United States Military Surveillance
  • United States: Regional Surveillance
  • OTHER COUNTRIES
  • Canada
  • Denmark
  • Finland
  • Greece
  • Iceland
  • EUROPEAN-WIDE SYSTEMS
  • GLOBAL SURVEILLANCE SYSTEMS
  • APPENDIX B American Society for Microbiology Recommendations
  • NATIONAL ANTIMICROBIAL SURVEILLANCE SYSTEM
  • A.Indications
  • B.Considerations
  • 1. National surveillance system should do the following
  • 2. Monitoring of organisms
  • 3. Geographic locations of participants
  • 4. Monitoring of populations
  • 5. Methods
  • 6. Locations of pathogen testing
  • 7. Format for data
  • 8. Data entry and analyses
  • 9. Frequency of analysis and access
  • 10. Organization of the surveillance system
  • 11. Immediate recommendations.
  • Appendix C Glossary and Acronyms
  • Appendix D Workshop Agenda.

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