Animal model studies on viral infections

Understanding viral replication and pathogenicity properties in infected individuals is a major mission of animal virology. Animal models are essential to analyze the in vivo viral characteristics and to develop countermeasures against viruses. To fight against a wide variety of viruses, basic studi...

Descripción completa

Detalles Bibliográficos
Otros Autores: Tomoyuki Miura (auth), Adachi, Akio, editor (editor), Miura, Tomoyuki, editor
Formato: Libro electrónico
Idioma:Inglés
Publicado: [Place of publication not identified] : Frontiers Media SA 2015
2015.
Colección:Frontiers in microbiology.
Materias:
Ver en Biblioteca Universitat Ramon Llull:https://discovery.url.edu/permalink/34CSUC_URL/1im36ta/alma991009432595506719
Tabla de Contenidos:
  • Animal model studies on viral infections
  • Animal models for human Herpesvirus 6 infection
  • Animal models for Ebola and Marburg virus infections
  • Hepatitis C virus infection and related liver disease: the quest for the best animal model
  • Can non-human primates serve as models for investigating Dengue disease pathogenesis?
  • A transgenic mouse model of human T cell Leukemia virus type-1 associated diseases
  • Mechanisms of pathogenesis induced by bovine leukemia virus as a model for human T-cell leukemia virus
  • Macaques as model hosts for studies of HIV-1 infection
  • Macaque-tropic Human Immunodeficiency Virus type 1: breaking out of the host restriction factors
  • Genetic similarity of circulating and small intestinal virus at the end stage of acute pathogenic Simian-Human Immunodeficiency Virus infection
  • A novel but simple method for generation of human dendritic cells from unfractionated peripheral blood mononuclear cells within 2 days: its application for induction of HIV-1-reactive CD4⁺ T cells in the hu-PBL SCID mice
  • Growth potentials of CCR5-Tropic/CXCR4-Tropic HIV-1mt clones in macaque cells
  • Sensitive detection of measles virus infection in the blood and tissues of humanized mouse by one-step quantitative RT-PCR
  • Quantification of viral infection dynamics in animal experiments
  • Transgenic expression of the human LEDGF/p75 gene relieves the species barrier against HIV-1 infection in mouse cells
  • Increased infectivity in human cells and resistant to antibody-mediated neutralization by truncation of the SIV gp41 cytoplasmic tail
  • Natural infection of murine novovirus in conventional and specific pathogen free laboratory mice
  • HPV18 E1̂ˆ̂E4 is assembled into aggresome-like compartment and involved in sequestration of viral oncoproteins.