90-day function outcome AGER Chinese elderly DNA methylation IL6R Medicine VTE risk prediction acute pancreatitis artificial intelligence atherosclerosis cognitive dysfunction complexity theory computer-aided diagnosis coronary artery disease coronary computed tomographic angiography coronary plaque craniopharyngioma deep learning dementia diabetic complication distal radius fracture entropy exposure to radiation facial phenotypes gene-gene interaction hip fracture incident diabetes interventions liver neoplasms machine learning